MySQL2 with native extensions ERROR: Failed to build gem native extension. (Gem::Installer::ExtensionBuildError)

Try with this, it worked for me:

sudo apt-get install libmysql-ruby libmysqlclient-dev

If you're using rvm, don't install libmysql-ruby because it's related with Ruby included in Ubuntu packages. It should be good enough with:

sudo apt-get install libmysqlclient-dev

In my case only unlinking symlinks and reinstalling mysql in brew helped:

brew unlink mysql
brew cleanup
brew install mysql
gem install mysql2

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