Open Google Chrome Specific Profile From Command Line Mac

To force a new profile window after Chrome has been launched:

open -n -a "Google Chrome" --args --profile-directory="<your profile>"

(where <your profile> is one of the Profile nn folder names found in ~/Library/Application Support/Google/Chrome/)

According to the manpage for open, the -n flag forces "a new instance of the application even if one is already running." You'll see second Chrome icon flash open briefly in the dock while the window loads but everything runs normal after that.

You could try the following:

/Applications/Google\ Chrome.app/Contents/MacOS/Google\ Chrome --args --profile-directory=Default

Referred from this answer.