Pandas fill missing values in dataframe from another dataframe

If you have two DataFrames of the same shape, then:

df[df.isnull()] = d2

Will do the trick.

Only locations where df.isnull() evaluates to True (highlighted in green) will be eligible for assignment.

In practice, the DataFrames aren't always the same size / shape, and transforming methods (especially .shift()) are useful.

Data coming in is invariably dirty, incomplete, or inconsistent. Par for the course. There's a pretty extensive pandas tutorial and associated cookbook for dealing with these situations.

As I just learned, there is a DataFrame.combine_first() method, which does precisely this, with the additional property that if your updating data frame d2 is bigger than your original df, the additional rows and columns are added, as well.

df = df.combine_first(d2)