pandas sort names a-z and numbers descengind code example

Example 1: df sort values

>>> df.sort_values(by=['col1'], ascending = False)
    col1 col2 col3
0   A    2    0
1   A    1    1
2   B    9    9
5   C    4    3
4   D    7    2
3   NaN  8    4

Example 2: dataframe, sort by columns

final_df = df.sort_values(by=['2'], ascending=False)