Prevent HTML file input from selecting files in Google Drive while using Android's native file chooser

I don't know a way to prevent the file picker to show these files, and I suspect there is none, but you can check quite easily if your code will be able to send it to your server by trying to read it.

Instead of reading the whole file, we can try to read only the first byte, by slicing the File object. Then to read it, we can simply call its arrayBuffer() method which will return a Promise, either resolving when the File is valid, or rejecting if we can't access the file:

const inp = document.querySelector('input');
inp.onchange = (evt) => {
  const file = inp.files[ 0 ];
  file.slice( 0, 1 ) // only the first byte
    .arrayBuffer() // try to read
    .then( () => {
      // success, we should be able to send that File
      console.log( 'should be fine' );
    } )
    .catch( (err) => {
      // error while reading
      console.log( 'failed to read' );
      inp.value = null; // remove invalid file?
    } );
};

<input type="file">

Note that even Files stored on disk may be modified by the user since they did pick it in your website, in that case, the upload would still fail. To handle this case too, you'd just have to perform the same exact test.

Note also that Blob.arrayBuffer() is quite recent and may require a polyfill, which is easily made or found on the internet.