Programmatically change screen resolution?

Yes, but its not part of .NET. You will need to use, invoke or write a wrapper to access the Win32 API.

See ChangeDisplaySettings and related function.

Here you can find a basic example.

You can use EnumDisplayDevices to figure out what displays you have available and EnumDisplaySettings to get a list of available resolutions for your displays. Use ChangeDisplaySettings to set the resolution you need.