distinct count with values of 2 columns in power bi code example

Example: dax count distinct based on 2 columns

--Without filters
Measure1 = COUNTROWS(GROUPBY(User,User[FNAME],User[Card ID],User[Health ID],User[Gender]))
--With filters
Measure2 = COUNTROWS(FILTER(GROUPBY(User,User[FNAME],User[Card ID],User[Health ID],User[Gender]),User[Gender]="M"))