How can i replace a number in pandas code example

Example 1: replace values of pandas column

df.loc[df['column'] == 'column_value', 'column'] = 'new_column_value'

Example 2: pandas find fifth caracter in field and change cell based on that number

data['result'] = data['result'].map(lambda x: x.lstrip('+-').rstrip('aAbBcC'))