how to replace all t characters in js code example

Example 1: how to replace all characters in a string javascript

const string = "a, b, c, d, e, f";
string.replace(/,/g, '');
console.log(string) //a b c d e f

Example 2: replace all character in string javascript

let a = "How to search and replace a char in a string";
while (a.search(" ", ""))
{
   a = a.replace(" ", "");
}
console.log(a);