how to replace letters with numbers in python code example

Example 1: replace number with string python

x = re.sub(r"\d+", "NUMB", str(x))       #Replaces digits with 'NUMB'

Example 2: python string replace letters with numbers

from string import ascii_letters

code = code = "1111702460830000Lu05"
code = "".join([str(ascii_letters.index(c)) if c in ascii_letters else c for c in code])
print(code)