Python Pandas Data frame creation

One of the correct ways would be to stack the array data from the input list holding those series into columns -

In [161]: pd.DataFrame(np.c_[s,t],columns = ["MUL1","MUL2"])
Out[161]: 
   MUL1  MUL2
0     1     2
1     2     4
2     3     6
3     4     8
4     5    10
5     6    12

Behind the scenes, the stacking creates a 2D array, which is then converted to a dataframe. Here's what the stacked array looks like -

In [162]: np.c_[s,t]
Out[162]: 
array([[ 1,  2],
       [ 2,  4],
       [ 3,  6],
       [ 4,  8],
       [ 5, 10],
       [ 6, 12]])

If remove columns argument get:

df = pd.DataFrame([s,t])

print (df)
   0  1  2  3   4   5
0  1  2  3  4   5   6
1  2  4  6  8  10  12

Then define columns - if columns not exist get NaNs column:

df = pd.DataFrame([s,t], columns=[0,'MUL2'])

print (df)
     0  MUL2
0  1.0   NaN
1  2.0   NaN

---

Better is use dictionary:

df = pd.DataFrame({'MUL1':s,'MUL2':t})

print (df)
   MUL1  MUL2
0     1     2
1     2     4
2     3     6
3     4     8
4     5    10
5     6    12

And if need change columns order add columns parameter:

df = pd.DataFrame({'MUL1':s,'MUL2':t}, columns=['MUL2','MUL1'])

print (df)
   MUL2  MUL1
0     2     1
1     4     2
2     6     3
3     8     4
4    10     5
5    12     6

More information is in dataframe documentation.

Another solution by concat - DataFrame constructor is not necessary:

df = pd.concat([s,t], axis=1, keys=['MUL1','MUL2'])

print (df)
   MUL1  MUL2
0     1     2
1     2     4
2     3     6
3     4     8
4     5    10
5     6    12