Python Pandas merge only certain columns

You want to use TWO brackets, so if you are doing a VLOOKUP sort of action:

df = pd.merge(df,df2[['Key_Column','Target_Column']],on='Key_Column', how='left')

This will give you everything in the original df + add that one corresponding column in df2 that you want to join.

You could merge the sub-DataFrame (with just those columns):

df2[list('xab')]  # df2 but only with columns x, a, and b

df1.merge(df2[list('xab')])