python win32 COM closing excel workbook

The the Workbook COM object has a Close() method. Basically, it should be something like:

xl = Dispatch('Excel.Application')
wb = xl.Workbooks.Open('New Workbook.xlsx')
# do some stuff
wb.Close(True) # save the workbook

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The above was just a skeleton here's some code that works on my machine against Office 2010:

from win32com.client import Dispatch
xl = Dispatch('Excel.Application')
wb = xl.Workbooks.Add()
ws = wb.Worksheets.Add()
cell = ws.Cells(1)
cell.Value = 'Some text'
wb.Close(True, r'C:\Path\to\folder\Test.xlsx')

Of course, that creates a new xlsx file. But then I'm able to successfully open and modify the file in the same session as follows:

wb = xl.Workbooks.Open(r'C:\Path\to\folder\Test.xlsx')
ws = wb.Worksheets(1)
cell = ws.Cells(2)
cell.Value = 'Some more text'
wb.Close(True)

Don't know if any of that helps...

You can also try to use the following code:

excel = Dispatch("Excel.Application")
excel.Visible = False
workbook = excel.Workbooks.Open(fileName)

# with saving
excel.DisplayAlerts = False
if saveAs:
    excel.ActiveWorkbook.SaveAs(fullFileNameToSave)
else:
    excel.ActiveWorkbook.Save()
excel.Quit()

#without saving

map(lambda book: book.Close(False), excel.Workbooks)
excel.Quit()

This function closes any opened excel file

import os

def closeFile():

    try:
        os.system('TASKKILL /F /IM excel.exe')

    except Exception:
        print("KU")

closeFile()