react hooks useEffect() cleanup for only componentWillUnmount?

You can use more than one useEffect().

For example, if my variable is data1, I can use all of this in my component:

useEffect( () => console.log("mount"), [] );
useEffect( () => console.log("data1 update"), [ data1 ] );
useEffect( () => console.log("any update") );
useEffect( () => () => console.log("data1 update or unmount"), [ data1 ] );
useEffect( () => () => console.log("unmount"), [] );

Since the cleanup is not dependent on the username, you could put the cleanup in a separate useEffect that is given an empty array as second argument.

Example

const { useState, useEffect } = React;

const ForExample = () => {
  const [name, setName] = useState("");
  const [username, setUsername] = useState("");

  useEffect(
    () => {
      console.log("effect");
    },
    [username]
  );

  useEffect(() => {
    return () => {
      console.log("cleaned up");
    };
  }, []);

  const handleName = e => {
    const { value } = e.target;

    setName(value);
  };

  const handleUsername = e => {
    const { value } = e.target;

    setUsername(value);
  };

  return (
    <div>
      <div>
        <input value={name} onChange={handleName} />
        <input value={username} onChange={handleUsername} />
      </div>
      <div>
        <div>
          <span>{name}</span>
        </div>
        <div>
          <span>{username}</span>
        </div>
      </div>
    </div>
  );
};

function App() {
  const [shouldRender, setShouldRender] = useState(true);

  useEffect(() => {
    setTimeout(() => {
      setShouldRender(false);
    }, 5000);
  }, []);

  return shouldRender ? <ForExample /> : null;
}

ReactDOM.render(<App />, document.getElementById("root"));
<script src="https://unpkg.com/react@16/umd/react.development.js"></script>
<script src="https://unpkg.com/react-dom@16/umd/react-dom.development.js"></script>

<div id="root"></div>