Reinstalling requirement file using pip

You can just go ahead and delete that directory, that's what the message is telling you.

Use:

pip uninstall Django==1.5.4

or

pip uninstall -r requirements.txt

If that still doesn't work, then go into you Python/Lib/site-packages directory where these packages live, and delete them. Then re-run

pip install -r requirements.txt

and that should work.