You must sign these kernel modules before using VirtualBox: vboxdrv vboxnetflt vboxnetadp code example
Example: If your system is using EFI Secure Boot you may need to sign the kernel modules (vboxdrv, vboxnetflt, vboxnetadp, vboxpci) before you can load them.
sudo -i
cd /root/module-signing
chmod 700 /root/module-signing/sign-vbox-modules
./sign-vbox-modules