MySQLdb/_mysql.c:46:10: fatal error: Python.h: No such file or directory #include "Python.h" ^~~~~~~~~~ compilation terminated. error: command 'x86_64-linux-gnu-gcc' failed with exit status 1\ code example

Example 1: Python.h: No such file or directory

For apt (Ubuntu, Debian...):

sudo apt-get install python-dev   # for python2.x installs
sudo apt-get install python3-dev  # for python3.x installs
For yum (CentOS, RHEL...):

sudo yum install python-devel   # for python2.x installs
sudo yum install python3-devel   # for python3.x installs
For dnf (Fedora...):

sudo dnf install python2-devel  # for python2.x installs
sudo dnf install python3-devel  # for python3.x installs
For zypper (openSUSE...):

sudo zypper in python-devel   # for python2.x installs
sudo zypper in python3-devel  # for python3.x installs
For apk (Alpine...):

# This is a departure from the normal Alpine naming
# scheme, which uses py2- and py3- prefixes
sudo apk add python2-dev  # for python2.x installs
sudo apk add python3-dev  # for python3.x installs
For apt-cyg (Cygwin...):

apt-cyg install python-devel   # for python2.x installs
apt-cyg install python3-devel  # for python3.x installs

Example 2: python.h missing

# `Python.h` is provided by the "python-dev" or "python3-dev" packages on debian/Ubuntu.
# On some sytems it will be "python-devel", "python2-devel" and/or "python3-devel"
sudo apt-get install python-dev python3-dev