Tools to make CSS sprites?

This will do 90% of the work for you: CSS Sprite Generator. You'll still need to edit the rules yourself, but the tool will give you the code fragments you need for the new CSS file.

Instant Sprite is an in-browser CSS sprite generator I'm working on. It's really fast, but doesn't have quite as many features as some of the others. It currently only works in Firefox or Chrome, since it uses JavaScript FileReader and HTML Canvas to generate the sprites inside the web browser without uploads.