UISegmentedControl change number of segments programmatically

Yes, you can use

removeSegmentAtIndex:(NSUInteger) animated:(BOOL)

And

insertSegmentWithTitle:(NSString *) atIndex:(NSUInteger) animated:(BOOL)

To replace the segments entirely, you can use the following function:

- (void)setSegments:(NSArray *)segments
{
    [segmentController removeAllSegments];

    for (NSString *segment in segments) {
        [segmentController insertSegmentWithTitle:segment atIndex:segmentController.numberOfSegments animated:NO];
    }
}

Hope this helps.