Using the reserved word "class" as field name in Django and Django REST Framework

You can rename field in the overloaded version of get_fields() method

class MySerializer(serializers.Serializer):
    class_ = serializers.ReadOnlyField()

    def get_fields(self):
        result = super().get_fields()
        # Rename `class_` to `class`
        class_ = result.pop('class_')
        result['class'] = class_
        return result

You can do it like below

class SpeciesSerializer(serializers.HyperlinkedModelSerializer):
    class Meta:
        model = Species
        fields = (
            'url', 'id', 'canonical_name', 'slug',  'species', 'genus',
            'subfamily', 'family', 'order','class', 'phylum',
            'ncbi_id', 'ncbi_taxonomy',
        )
        read_only_fields = ('slug',)
        extra_kwargs = {
            'url': {'lookup_field': 'slug'}
        }

SpeciesSerializer._declared_fields["class"] = serializers.CharField(source="class_name")

As explained in below answer

https://stackoverflow.com/a/47717441/2830850

Other software developers in the field of Bioinformatics might be interested in a solution of this problem, so I post here my approach as suggested by Alasdair.

The goal is to create a model for a living species, for the sake of simplicity let's say an animal, and create an endpoint with Django REST Framework representing the correct taxonomic ranks.

models.py

from django.db import models

class Animal(models.Model):
    canonical_name = models.CharField(max_length=100, unique=True)
    species = models.CharField(max_length=60, unique=True)
    genus = models.CharField(max_length=30)
    family = models.CharField(max_length=30)
    order = models.CharField(max_length=30)
    # we can't use class as field name
    class_name = models.CharField('Class', db_column='class', max_length=30)
    phylum = models.CharField(max_length=30)
    # we don't need to define kingdom and domain
    # it's clear that it is an animal and eukaryote

    def __str__(self):
        return '{} ({})'.format(self.canonical_name, self.species)

serializers.py

from collections import OrderedDict

from rest_framework import serializers

from .models import Species

class SpeciesSerializer(serializers.HyperlinkedModelSerializer):
    class Meta:
        model = Animal
        fields = ('url', 'id', 'canonical_name', 'species', 'genus',
            'subfamily', 'family', 'order', 'class_name', 'phylum')

    def to_representation(self, obj):
        # call the parent method and get an OrderedDict
        data = super(SpeciesSerializer, self).to_representation(obj)
        # generate a list of the keys and replace the key 'class_name'
        keys = list(data.keys())
        keys.insert(keys.index('class_name'), 'class')
        keys.remove('class_name')
        # remove 'class_name' and assign its value to a new key 'class'
        class_name = data.pop('class_name')
        data.update({'class': class_name})
        # create new OrderedDict with the order given by the keys
        response = OrderedDict((k, data[k]) for k in keys)
        return response

The method to_representation helps us to manipulate the output. I have put some extra work here to get the taxonomic ranks in the desired order.

Thus for the red fox the output looks like this:

Red fox (Vulpes vulpes)

{
    "url": "http://localhost:8000/animal/1",
    "id": 1,
    "canonical_name": "Red fox",
    "species": "Vulpes vulpes",
    "genus": "Vulpes",
    "family": "Canidae",
    "order": "Carnivora",
    "class": "Mammalia",
    "phylum": "Chordata"
}

It is a simplified example and in reality you'd have many more fields or possibly a model for every taxonomic rank, but somewhere you might come across the conflict between the reserved word class and the taxonomic rank class.
I hope this can help other people too.