Utility to scale window content to fullscreen
For windowed mode, you might want to use the magnifier from windows' accessibility tools (or some freeware equivalent) in fullscreen mode. I don't know if you can set it to exactly zoom in on the game window though.
Check out IntegerScaler. It scales up any window to match the screen's size and it was the only program that worked for me without the mouse messing up in my game.