Visual Studio refuses to forget breakpoints?

go to Debug menu then Delete All Breakpoints Ctrl+Shift+F9

The problem is that child breakpoints of your breakpoints persist. Child breakpoints are created (in certain situations) when setting breakpoints during a debug session.

A surefire way of deleting a breakpoint (and children) is to manually look for it in the breakpoint window, and delete it from there. (Select the top node of the entry, hit Delete.)

If you're running an (old) version of Visual Studio that supports VBScript macros, you could run the macro posted here (between debug sessions), to remove child breakpoints. This will make removing breakpoints by clicking the glyph somewhat more effective and predictable, but it continues to be problematic and awkward.