What is the easiest way to remove all packages installed by pip?

I've found this snippet as an alternative solution. It's a more graceful removal of libraries than remaking the virtualenv:

pip freeze | xargs pip uninstall -y

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In case you have packages installed via VCS, you need to exclude those lines and remove the packages manually (elevated from the comments below):

pip freeze | grep -v "^-e" | xargs pip uninstall -y

This will work for all Mac, Windows, and Linux systems. To get the list of all pip packages in the requirements.txt file (Note: This will overwrite requirements.txt if exist else will create the new one, also if you don't want to replace old requirements.txt then give different file name in the all following command in place requirements.txt).

pip freeze > requirements.txt

Now to remove one by one

pip uninstall -r requirements.txt

If we want to remove all at once then

pip uninstall -r requirements.txt -y

If you're working on an existing project that has a requirements.txt file and your environment has diverged, simply replace requirements.txt from the above examples with toberemoved.txt. Then, once you have gone through the steps above, you can use the requirements.txt to update your now clean environment.

And For single command without creating any file (As @joeb suggested).

pip uninstall -y -r <(pip freeze)