What is the most productive combination of powers to use in Quickplay+ mode?

I have played this game far too long and far too much, and I still enjoy it.

That being said, I have experimented quite a lot with these powers. Basically, this will depend on the length and difficulty of the song, as well as the amount of notes and whether or not you can/will streak on it.

There is no pair that trumps the rest, but below are some guide lines:

• If the song is short, I would suggest using Axel, Resurrector+, since it grants them regardless of length.
• If the song is long, and you can streak, it could be useful to use Lars, Multiplier Extender+
• If the song is long and contains lots of notes that are streak-able, use Echo, Star Power Generator+

The above STRONGLY applies to guitar. Also, always remember that the higher the skill level, the more the notes, the bigger the score! Although, this only works that way IF THE PLAYER CAN PLAY that skill level. Rather get 90% and above on Hard than getting less than 60% on Expert - Streaking is important!

My personal bests are done with 'Pandora, Star Power Nova+ (Star Power multiplier is 6x)' and 'Echo, Star Power Generator+ (get 10% Star Power for every 10-note streak)' on expert, since I streak a lot on expert, which gives a lot of notestreaks (which gives a lot of Star Power), which allows me to keep my Star Power active through almost the whole song, meaning I get a constant multiplier of 24x (4x6)!!

Using Echo and Pandora, I cannot remember ever getting less than 14 stars ever.

Hope this helps*