What perks apply to the Syringer Rifle in Fallout 4?
According to the Syringer page on Nukapedia,
The Syringer does not benefit from Quick Hands, Rifleman, Mister Sandman, Bloody Mess, or Ninja, but Sniper 1 and 3 both work.
It's not automatic or a pistol, so Gunslinger and Commando wouldn't work either.
Sniper 1 is
It's all about focus. You have improved control and can hold your breath longer when aiming with scopes.
and Sniper 3 is
Non-automatic, scoped rifles gain +25% accuracy to head shot in V.A.T.S.
I can't find any information on critical hits with the Syringer at all. Not sure if it has any effect. Needs testing.
If luck improves your % chance for the rifle's random effects, I see no evidence to that effect.
According to the wikia, there are confirmed perks that do not work with the Syringer...
The Syringer does not benefit from Quick Hands, Rifleman, Mister Sandman, Bloody Mess, or Ninja, but Sniper 1 and 3 both work.
According to the wiki:
The Syringer does not benefit from Quick Hands, Rifleman, Mister Sandman, Bloody Mess, or Ninja, but Sniper 1 and 3 both work.