Wine Install - Do I need Mono, Gecko, etc

Mono

You need Mono to run certain applications and components.

It is recommended to install the Microsoft core fonts, some applications require it to work properly.

I suggest you to install PlayOnLinux, so you can manage your Wine prefixes easily by installing the components required for each one.

For example, if you want to install Microsoft Office, PlayOnLinux already has a script which automatically installs the required complements and packages.

You can install mono by using:

sudo apt install mono-complete

or (for Ubuntu versions prior to 16.04)

sudo apt-get install mono-complete

Gecko

For Gecko, check https://wiki.winehq.org/Gecko