WPF with C++, is it possible?

Yes, you can develop a GUI using WPF framework in Managed C+ or C++/CLI. But they're not Standard C++, hence not cross-platform.

If you just want a GUI for your application written in C++, then you may try Qt as well. The advantage in Qt is that its completely in C++. Not Microsoft Managed C++. The second advantage is that its cross-platform toolkit. That means, you can run your app in Windows, Linux, Mac, and on other machines as well.

Have a look at its documentation

• Qt Reference Documentation

It has lots of tools for fast development such as Qt Creator, Qt Designer and others. You can see all of them by browsing the above link.

You can use WPF in a managed C++ project, but you're better off keeping your C++ in a separate assembly and referencing it from a C# or VB WPF project.