BTRFS, sector alignment and Advance Format Disks
From my experience, letting btrfs take over a whole disk with no partitions will not result in proper logical/physical sector alignment. I've tried this with 3.14.1; latter versions may do this differently (current release is 3.18.x).
My suggestion is to use properly aligned GPT partitions and tell BTRFS to use a 4K sector size with mkfs.btrfs --sectorsize.