GetModuleHandle(NULL) vs hInstance

In an EXE, it does not make any difference. hInstance from WinMain() and GetModuleHandle(NULL) both refer to the same HINSTANCE (the module of the .exe file). But it does make a difference if you are creating windows inside of a DLL instead, since you have to use the DLL's hInstance but GetModuleHandle(NULL) will still return the HINSTANCE of the EXE that loaded the DLL.

HMODULE WINAPI GetModuleHandle( _In_opt_  LPCTSTR lpModuleName );

Give the module handle of the module name passed.If you are passing NULL, the you get the module handle of the EXE which is currently running. If you specifically name the module name, you get the module handle of that dll which is mapped to the process address space. The use is that when you are trying to call a function exported by the dll, or trying to use a dialog template in side that dll.At that time if you use the HMODULE returned form GetMoudleHandle(NULL) your code wont work.

One potential gain you get from using GetModuleHandle(NULL) over directly using the WinMain HINSTANCE comes more from architecture. If you want to provide a platform-independent system that runs on linux/windows/whatever you can have a layer that does platform-dependent translations. If that's the case you don't want platform dependent objects such as HINSTANCE showing up in the main application code. So, to circumvent that platform-dependence I put GetModuleHandle(NULL) in the constructor of the platform-dependent class which has the same effect that direct use of the WinMain HINSTANCE does but that abstracts that specific functionality out of the main codebase itself.