How to clear AlamofireImage setImageWithURL cache

Hope this might help you:

let URL = NSURL(string: "https://cdn.domain.com/profile/image.jpg")!
let imageDownloader = UIImageView.af_sharedImageDownloader
let imageCache = imageDownloader.imageCache
// Setting CachePolicy as reloadIgnoringLocalCacheData so that it won't use URL Cache next time when it is hitting same URL
let urlRequest = URLRequest(url: URL, cachePolicy: URLRequest.CachePolicy.reloadIgnoringLocalCacheData)
        // Clear the Image from the in-memory cache      
        let _ = imageCache?.removeImage(for: urlRequest, withIdentifier: nil)
        imageView.af_setImage(withURLRequest: urlRequest, placeholderImage: UIImage(named: "placeholder"), completion: { (response) in
            self.imageView.image = response.result.value
        })

Swift3 and AlamofireImage 3.x It appears removeImage does all that is needed.

        // Clear what is in the cache, this will force a refresh to ensure fresh image is loaded next time
        let urlRequest = Foundation.URLRequest(url: validUrl)
        let imageDownloader = UIImageView.af_sharedImageDownloader
        if let imageCache2 = imageDownloader.imageCache {
            _ = imageCache2.removeImage(for: urlRequest, withIdentifier: nil)
        }

You need to remove the image from the in-memory cache as well as the on-disk cache. You can do this as follows:

func clearImageFromCache() {
    let URL = NSURL(string: "https://cdn.domain.com/profile/image.jpg")!
    let URLRequest = NSURLRequest(URL: URL)

    let imageDownloader = UIImageView.af_sharedImageDownloader

    // Clear the URLRequest from the in-memory cache
    imageDownloader.imageCache?.removeImageForRequest(URLRequest, withAdditionalIdentifier: nil)

    // Clear the URLRequest from the on-disk cache
    imageDownloader.sessionManager.session.configuration.URLCache?.removeCachedResponseForRequest(URLRequest)
}

Currently, the URLCache can only be cleared in this manner on the master branch. I just pushed f35e4748 which allows access to the underlying sessionManager in the ImageDownloader. This is not yet available in an actual release yet, but should be here sometime this week.