How to remove select2 from dom

You need to use destroy method on select2. See the Documentation

i.e

 $("#e1").select2('destroy'); 

Version 4.0

$element.data('select2').destroy();

That work for me!

var $select = $('.select2').select2();
//console.log($select);
$select.each(function(i,item){
  //console.log(item);
  $(item).select2("destroy");
});