How to show MessageBox on asp.net?

There is pretty concise and easy way:

Response.Write("<script>alert('Your text');</script>");

MessageBox doesn't exist in ASP.NET. If you need functionality in the browser, like showing a message box, then you need to opt for javascript. ASP.NET provides you with means to inject javascript which gets rendered and executed when the html sent to the browser's loaded and displayed. You can use the following code in the Page_Load for example:

Type cstype = this.GetType();

// Get a ClientScriptManager reference from the Page class.
ClientScriptManager cs = Page.ClientScript;

// Check to see if the startup script is already registered.
if (!cs.IsStartupScriptRegistered(cstype, "PopupScript"))
{
    String cstext = "alert('Hello World');";
    cs.RegisterStartupScript(cstype, "PopupScript", cstext, true);
}

This sample's taken from MSDN.