How do I split a string with multiple separators in JavaScript?

You can pass a regex into JavaScript's split() method. For example:

"1,2 3".split(/,| /) 
["1", "2", "3"]

Or, if you want to allow multiple separators together to act as one only:

"1, 2, , 3".split(/(?:,| )+/) 
["1", "2", "3"]

You have to use the non-capturing (?:) parenthesis, because otherwise it gets spliced back into the result. Or you can be smart like Aaron and use a character class.

Examples tested in Safari and Firefox.

Pass in a regexp as the parameter:

js> "Hello awesome, world!".split(/[\s,]+/)
Hello,awesome,world!

Edited to add:

You can get the last element by selecting the length of the array minus 1:

>>> bits = "Hello awesome, world!".split(/[\s,]+/)
["Hello", "awesome", "world!"]
>>> bit = bits[bits.length - 1]
"world!"

... and if the pattern doesn't match:

>>> bits = "Hello awesome, world!".split(/foo/)
["Hello awesome, world!"]
>>> bits[bits.length - 1]
"Hello awesome, world!"