How to trigger from Python playing of a WAV or MP3 audio file on a Mac?

If you want to do away with external dependencies entirely, and are running OS X 10.5+, you can use the included command-line audio player, afplay, along with the subprocess module.

I haven't tested it, but this should work:

import subprocess
audio_file = "/full/path/to/audio.wav"

return_code = subprocess.call(["afplay", audio_file])

As far as I know PyGame is the most portable way to play music: http://www.pygame.org/docs/ref/music.html

You can find its package here: http://www.pygame.org/download.shtml