TypeError: 'Response' object has no attribute '__getitem__'

The response object is not a dictionary, you cannot use indexing on it.

If the API returns a JSON response, you need to use the response.json() method to decode it to a Python object:

data = response.json()
print("respone is: ", data['result'])

Note that you don't have to encode the request JSON data either; you could just use the json argument to the request.post() method here; this also sets the Content-Type header for you:

response = requests.post(url, json=payload, auth=auth)

Last but not least, if the API uses JSONRPC as the protocol, you could use the jsonrpc-requests project to proxy method calls for you:

from jsonrpc_requests import Server

url = "http://public.coindaddy.io:4000/api/"
server = Server(url, auth=('rpc', '1234'))

result = server.get_running_info()

Just change your source code a bit like this :

 response = requests.post(url, json=json.dumps(payload), headers=headers,   auth=auth).json()

 print("respone is: ", response['result'].encode('utf-8'))

It's true that response object alone can't be indexed instead for that purpose you need to return info in json format (in order parse response information ) which you can do so using json() and Here in order to get proper string you must encode it with utf-8 (other wise your output will be something like this -u'LikeThis)