Is it possible to create a generic @helper method with Razor?

This is possible to achieve inside a helper file with the @functions syntax but if you want the razor-style readability you are referring to you will also need to call a regular helper to do the HTML fit and finish.

Note that functions in a Helper file are static so you would still need to pass in the HtmlHelper instance from the page if you were intending to use its methods.

e.g. Views\MyView.cshtml:

@MyHelper.DoSomething(Html, m=>m.Property1)
@MyHelper.DoSomething(Html, m=>m.Property2)
@MyHelper.DoSomething(Html, m=>m.Property3)

App_Code\MyHelper.cshtml:

@using System.Web.Mvc;
@using System.Web.Mvc.Html;
@using System.Linq.Expressions;
@functions
{
    public static HelperResult DoSomething<TModel, TItem>(HtmlHelper<TModel> html, Expression<Func<TModel, TItem>> expr)
    {
        return TheThingToDo(html.LabelFor(expr), html.EditorFor(expr), html.ValidationMessageFor(expr));
    }
}
@helper TheThingToDo(MvcHtmlString label, MvcHtmlString textbox, MvcHtmlString validationMessage)
{
    <p>
        @label
        <br />
        @textbox
        @validationMessage
    </p>
}
...

No, this is not currently possible. You could write a normal HTML helper instead.

public static MvcHtmlString DoSomething<T, U>(
    this HtmlHelper htmlHelper, 
    Expression<Func<T, U>> expr
) where T : class
{
    ...
}

and then:

@(Html.DoSomething<SomeModel, string>(x => x.SomeProperty))

or if you are targeting the model as first generic argument:

public static MvcHtmlString DoSomething<TModel, TProperty>(
    this HtmlHelper<TModel> htmlHelper, 
    Expression<Func<TModel, TProperty>> expr
) where TModel : class
{
    ...
}

which will allow you to invoke it like this (assuming of course that your view is strongly typed, but that's a safe assumption because all views should be strongly typed anyways :-)):

@Html.DoSomething(x => x.SomeProperty)