.Net MVC 4 Project fails with Event Log Error "The Module DLL C:\WINDOWS\system32\inetsrv\aspnetcore.dll failed to load. The data is the error."

Here's the easiest solution:

1. Search Cortana for Programs and Features to open the legacy Control Panel's installed applications list.
2. Find and click the entry for Microsfot .NET Core 1.0.0 - VS 2015 Tooling ...
   • My version is "Preview 2"... though if they don't fix this, you may have a newer version
3. Click Change.
4. Click Repair.

The source of this problem seems to be the build upgrade process for Windows 10, where it re-installs IIS... while it copies over all the site settings to the new applicationHost.config, it seems to break any non-standard modules you previously had installed. For example, this same problem also affects the URL Rewrite 2 module (which is also fixed by running a repair).

Hopefully the team at Microsoft who works on maintaining the IIS config between build updates will get a chance to fix this (they're tracking this bug on github here). Until then, you have to do this repair after installing any new Windows builds.

UPDATE: This bug has been fixed in Windows 10 Insider Build 15002, and will be released as part of the Windows 10 Creators Update on April 11, 2017. So, once you've solved this by following the steps above, you shouldn't run into it again with the next major Windows 10 update.

Download the DotNetCore.1.0.0.RC2-SDK.Preview1-x64.exe, execute and uninstall. After, go to Programs and Features e Repair the Microsoft.NET Core 1.0.0 RC2 - VS 2015 Tooling Preview 1. Work for me.

I too faced the same issue. As a workaround, I marked Enable 32-Bit Application as false in application pool.

For more details, please check at below link https://github.com/aspnet/Home/issues/1583