npx create-react-app not working "Must use import to load ES Module:"

this issue is fixed with 2.2.2 version of is-promise package. If you still experience problems creating new CRA, consider npm install -g --force create-react-app

If even then bug is still present, please comment your issue to this github issue

I would:

1. Restart the machine. Ensure you log out of your session if needed
2. Re-install Create React App
3. Uninstall yarn and reinstall
4. Reinstall node, ensure you use a newer version
5. Use a different network connection, maybe something is being blocked by a firewall