Pandas - Compute z-score for all columns

Build a list from the columns and remove the column you don't want to calculate the Z score for:

In [66]:
cols = list(df.columns)
cols.remove('ID')
df[cols]

Out[66]:
   Age  BMI  Risk  Factor
0    6   48  19.3       4
1    8   43  20.9     NaN
2    2   39  18.1       3
3    9   41  19.5     NaN
In [68]:
# now iterate over the remaining columns and create a new zscore column
for col in cols:
    col_zscore = col + '_zscore'
    df[col_zscore] = (df[col] - df[col].mean())/df[col].std(ddof=0)
df
Out[68]:
   ID  Age  BMI  Risk  Factor  Age_zscore  BMI_zscore  Risk_zscore  \
0  PT    6   48  19.3       4   -0.093250    1.569614    -0.150946   
1  PT    8   43  20.9     NaN    0.652753    0.074744     1.459148   
2  PT    2   39  18.1       3   -1.585258   -1.121153    -1.358517   
3  PT    9   41  19.5     NaN    1.025755   -0.523205     0.050315   

   Factor_zscore  
0              1  
1            NaN  
2             -1  
3            NaN  

Using Scipy's zscore function:

df = pd.DataFrame(np.random.randint(100, 200, size=(5, 3)), columns=['A', 'B', 'C'])
df

|    |   A |   B |   C |
|---:|----:|----:|----:|
|  0 | 163 | 163 | 159 |
|  1 | 120 | 153 | 181 |
|  2 | 130 | 199 | 108 |
|  3 | 108 | 188 | 157 |
|  4 | 109 | 171 | 119 |

from scipy.stats import zscore
df.apply(zscore)

|    |         A |         B |         C |
|---:|----------:|----------:|----------:|
|  0 |  1.83447  | -0.708023 |  0.523362 |
|  1 | -0.297482 | -1.30804  |  1.3342   |
|  2 |  0.198321 |  1.45205  | -1.35632  |
|  3 | -0.892446 |  0.792025 |  0.449649 |
|  4 | -0.842866 | -0.228007 | -0.950897 |

If not all the columns of your data frame are numeric, then you can apply the Z-score function only to the numeric columns using the select_dtypes function:

# Note that `select_dtypes` returns a data frame. We are selecting only the columns
numeric_cols = df.select_dtypes(include=[np.number]).columns
df[numeric_cols].apply(zscore)

|    |         A |         B |         C |
|---:|----------:|----------:|----------:|
|  0 |  1.83447  | -0.708023 |  0.523362 |
|  1 | -0.297482 | -1.30804  |  1.3342   |
|  2 |  0.198321 |  1.45205  | -1.35632  |
|  3 | -0.892446 |  0.792025 |  0.449649 |
|  4 | -0.842866 | -0.228007 | -0.950897 |

If you want to calculate the zscore for all of the columns, you can just use the following:

df_zscore = (df - df.mean())/df.std()