Practical Solution For Giant Spike Balls

According to http://terraria.gamepedia.com/Spike_Ball:

They spawn and despawn off-screen like any other enemy — if you leave a room and return later, it will have a different configuration of Spike Balls.

So unfortunately, any steps you take to control an individual spike ball will be rendered moot when you leave and come back because the spike ball will almost certainly have moved.

EDIT: Here's a way to potentially use this for your benefit: If there's a Spike Ball in an especially difficult position (say, so that it makes it impossible to get to a chest), you can leave the area and come back later. Unfortunately, since navigating the dungeon is nasty enough, this will only help with the worst Spike Balls.


According to here: Spike Ball

"It is possible to hurt and kill the Spike Ball with the Thorns buff using the Thorns Potion."

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Terraria