Selecting multiple columns in a Pandas dataframe

The column names (which are strings) cannot be sliced in the manner you tried.

Here you have a couple of options. If you know from context which variables you want to slice out, you can just return a view of only those columns by passing a list into the __getitem__ syntax (the []'s).

df1 = df[['a', 'b']]

Alternatively, if it matters to index them numerically and not by their name (say your code should automatically do this without knowing the names of the first two columns) then you can do this instead:

df1 = df.iloc[:, 0:2] # Remember that Python does not slice inclusive of the ending index.

Additionally, you should familiarize yourself with the idea of a view into a Pandas object vs. a copy of that object. The first of the above methods will return a new copy in memory of the desired sub-object (the desired slices).

Sometimes, however, there are indexing conventions in Pandas that don't do this and instead give you a new variable that just refers to the same chunk of memory as the sub-object or slice in the original object. This will happen with the second way of indexing, so you can modify it with the .copy() method to get a regular copy. When this happens, changing what you think is the sliced object can sometimes alter the original object. Always good to be on the look out for this.

df1 = df.iloc[0, 0:2].copy() # To avoid the case where changing df1 also changes df

To use iloc, you need to know the column positions (or indices). As the column positions may change, instead of hard-coding indices, you can use iloc along with get_loc function of columns method of dataframe object to obtain column indices.

{df.columns.get_loc(c): c for idx, c in enumerate(df.columns)}

Now you can use this dictionary to access columns through names and using iloc.

As of version 0.11.0, columns can be sliced in the manner you tried using the .loc indexer:

df.loc[:, 'C':'E']

gets the same columns as

df[['C', 'D', 'E']] # Mind, this makes a copy.

or

df.loc[:, ['C', 'D', 'E']] # This does not make a copy (better).

and returns columns C through E.

---

A demo on a randomly generated DataFrame:

import pandas as pd
import numpy as np
np.random.seed(5)
df = pd.DataFrame(np.random.randint(100, size=(100, 6)),
                  columns=list('ABCDEF'),
                  index=['R{}'.format(i) for i in range(100)])
df.head()

Out:
     A   B   C   D   E   F
R0  99  78  61  16  73   8
R1  62  27  30  80   7  76
R2  15  53  80  27  44  77
R3  75  65  47  30  84  86
R4  18   9  41  62   1  82

To get the columns from C to E (note that unlike integer slicing, E is included in the columns):

df.loc[:, 'C':'E']

Out:
      C   D   E
R0   61  16  73
R1   30  80   7
R2   80  27  44
R3   47  30  84
R4   41  62   1
R5    5  58   0
...

The same works for selecting rows based on labels. Get the rows R6 to R10 from those columns:

df.loc['R6':'R10', 'C':'E']

Out:
      C   D   E
R6   51  27  31
R7   83  19  18
R8   11  67  65
R9   78  27  29
R10   7  16  94

.loc also accepts a Boolean array so you can select the columns whose corresponding entry in the array is True. For example, df.columns.isin(list('BCD')) returns array([False, True, True, True, False, False], dtype=bool) - True if the column name is in the list ['B', 'C', 'D']; False, otherwise.

df.loc[:, df.columns.isin(list('BCD'))]

Out:
      B   C   D
R0   78  61  16
R1   27  30  80
R2   53  80  27
R3   65  47  30
R4    9  41  62
R5   78   5  58
...