Subject Alternative Name Missing & ERR_SSL_VERSION_OR_CIPHER_MISMATCH

Thanks Oleg for nice solution. In my case, the URI is specified as an IP address rather than a hostname, finally, i get the solution from here.

I edit @Oleg's MyCompanyLocalhost.ext, from

subjectAltName = @alt_names
extendedKeyUsage = serverAuth

[alt_names]
DNS.1   = localhost
DNS.2   = mypc.mycompany.com

to

subjectAltName = @alt_names
extendedKeyUsage = serverAuth

[alt_names]

DNS.1 = domain.com 
# IP address
IP.1 = 192.168.2.221
IP.2 = 127.0.0.1

I suggest the following solution: create self-signed CA certificate and the web server certificate signed by this CA. When you install this small chain to your web server it will work with Chrome.

Create configuration file for your CA MyCompanyCA.cnf with contents (you can change it to your needs):

[ req ]
distinguished_name  = req_distinguished_name
x509_extensions     = root_ca

[ req_distinguished_name ]
countryName             = Country Name (2 letter code)
countryName_min         = 2
countryName_max         = 2
stateOrProvinceName     = State or Province Name (full name)
localityName            = Locality Name (eg, city)
0.organizationName      = Organization Name (eg, company)
organizationalUnitName  = Organizational Unit Name (eg, section)
commonName              = Common Name (eg, fully qualified host name)
commonName_max          = 64
emailAddress            = Email Address
emailAddress_max        = 64

[ root_ca ]
basicConstraints            = critical, CA:true

Create the extensions configuration file MyCompanyLocalhost.ext for your web server certificate:

subjectAltName = @alt_names
extendedKeyUsage = serverAuth

[alt_names]
DNS.1   = localhost
DNS.2   = mypc.mycompany.com

Then execute the following commands:

openssl req -x509 -newkey rsa:2048 -out MyCompanyCA.cer -outform PEM -keyout MyCompanyCA.pvk -days 10000 -verbose -config MyCompanyCA.cnf -nodes -sha256 -subj "/CN=MyCompany CA"

openssl req -newkey rsa:2048 -keyout MyCompanyLocalhost.pvk -out MyCompanyLocalhost.req -subj /CN=localhost -sha256 -nodes
openssl x509 -req -CA MyCompanyCA.cer -CAkey MyCompanyCA.pvk -in MyCompanyLocalhost.req -out MyCompanyLocalhost.cer -days 10000 -extfile MyCompanyLocalhost.ext -sha256 -set_serial 0x1111

As result you will get MyCompanyCA.cer, MyCompanyLocalhost.cer and MyCompanyLocalhost.pvk files that you can install to the web server.

How to check that it works with Chrome before installing certificates to the web server. Execute the following command on your local PC to run web server simulator:

openssl s_server -accept 15000 -cert MyCompanyLocalhost.cer -key MyCompanyLocalhost.pvk -CAfile MyCompanyCA.cer -WWW

Then you can access this page at https://localhost:15000/ You will see an error that MyCompanyLocalhost.cer is not trusted, if you want to eliminate this error also - then install MyCompanyCA.cer to the certificate trusted list of your OS.