VS 2017 - Very slow (laggy) when debugging
After some additional investigation I found this thread Unchecking Enable Diagnostic Tools while debugging in Tools → Options → Debugging → General did the trick!
Unchecking Enable JavaScript debugging for ASP.NET in
Tools → Options → Debugging → General
makes a huge difference in performance.
Hiding the Threads window did the trick for me.
I have tried disabling few things myself just to see what is causing it. The only thing that did work for me is Tools > Options > Debugging > General > "Enable JavaScript debugging for ASP.NET (Chrome and IE)".
I'm using VS2017 Enterprise v15.2 for Asp.net WebForms.
If disable Diagnostic Tools don't fix the problem try to disable IntelliTrace, Unchecking Enable IntelliTrace, in Tools -> Options -> IntelliTrace. Work for me.