What is the best way to connect and use a sqlite database from C#

I'm with, Bruce. I AM using http://system.data.sqlite.org/ with great success as well. Here's a simple class example that I created:

using System;
using System.Text;
using System.Data;
using System.Data.SQLite;

namespace MySqlLite
{
      class DataClass
      {
        private SQLiteConnection sqlite;

        public DataClass()
        {
              //This part killed me in the beginning.  I was specifying "DataSource"
              //instead of "Data Source"
              sqlite = new SQLiteConnection("Data Source=/path/to/file.db");

        }

        public DataTable selectQuery(string query)
        {
              SQLiteDataAdapter ad;
              DataTable dt = new DataTable();

              try
              {
                    SQLiteCommand cmd;
                    sqlite.Open();  //Initiate connection to the db
                    cmd = sqlite.CreateCommand();
                    cmd.CommandText = query;  //set the passed query
                    ad = new SQLiteDataAdapter(cmd);
                    ad.Fill(dt); //fill the datasource
              }
              catch(SQLiteException ex)
              {
                    //Add your exception code here.
              }
              sqlite.Close();
              return dt;
  }
}

There is also an NuGet package: System.Data.SQLite available.

ADO.NET 2.0 Provider for SQLite has over 200 downloads every day, so I think you are safe using that one.

I've used this with great success:

http://system.data.sqlite.org/

Free with no restrictions.

(Note from review: Original site no longer exists. The above link has a link pointing the the 404 site and has all the info of the original)

--Bruce