How to check if a app is in debug or release

Personally I don't like the way #if DEBUG changes the layout. I do it by creating a conditional method that is only called when in debug mode and pass a boolean by reference.

[Conditional("DEBUG")]
private void IsDebugCheck(ref bool isDebug)
{
    isDebug = true;
}
 
public void SomeCallingMethod()
{ 
    bool isDebug = false;
    IsDebugCheck(ref isDebug);

    //do whatever with isDebug now
}

static class Program
{
    public static bool IsDebugRelease
    {
        get
        {
 #if DEBUG
            return true;
 #else
            return false;
 #endif
        }
     }
 }

Though, I tend to agree with itowlson.

At compile time or runtime? At compile time, you can use #if DEBUG. At runtime, you can use [Conditional("DEBUG")] to indicate methods that should only be called in debug builds, but whether this will be useful depends on the kind of changes you want to make between debug and release builds.