How can I change all the Windows 10 privacy settings without dozens of clicks?

There are some GUI tools out there that promise to change these settings. One I couldn't install because Microsoft Security Essentials claims it is containing a Trojan, the other one changes only a very limited set of settings.

So I wrote my own.

It's a single PowerShell script file that either sets one of three predefined sets of settings or allows the user to specify all the settings to be changed.

So if you are not afraid of the command line, you can try this and see exactly what is going on by looking at the script code.

Set-Privacy.ps1 on GitHub

There's O&O ShutUp10. It ranks really highly on duckduckgo and I've seen it mentioned in a few other places like thewindowsclub.com. Right now, though, there doesn't seem to be a clear frontrunner in this space. So, maybe just try a bunch of the suggestions in the second link?